Publications List

The latest articles.
Authors’ name links to abstract on PubMed
last update 2024.3.15

2024

Shiraishi T, Katayama Y, Nishiyama M, Shoji H, Miyakawa T, Mizoo T, Matsumoto A, Hijikata A, Shirai T, Mayanagi K, Nakayama KI.
The complex etiology of autism spectrum disorder due to missense mutations of CHD8.
Mol. Psychiatry,  Online ahead of print, 2024.

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2024

Shiraishi T, Katayama Y, Nishiyama M, Shoji H, Miyakawa T, Mizoo T, Matsumoto A, Hijikata A, Shirai T, Mayanagi K, Nakayama KI.
The complex etiology of autism spectrum disorder due to missense mutations of CHD8.
Mol. Psychiatry,  Online ahead of print, 2024.

Sugiyama S., Yumimoto K., Fujinuma S., Nakayama KI.
Identification of effective CCR2 inhibitors for cancer therapy using humanized mice.
J. Biochem., 175: 195-204, 2024.

Hagiwara H., (incl. Nakayama KI.), Miyagawa T.
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
eLife, 12:RP89376, 2024.

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2001

No. 1, Times Cited: 1343.

Nakayama K., Ishida N., Shirane M., Inomata A., Inoue T., Shishido N., Horii I., Loh DY., Nakayama KI.
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.
Cell, 85: 707-20, 1996.

No. 2, Times Cited: 976.

Nakayama KI., Nakayama K.
Ubiquitin ligases: cell-cycle control and cancer.
Nature Rev. Cancer, 6: 369-81, 2006.

No. 3, Times Cited: 602.

Nakayama K., Nagahama H., Minamishima YA., Matsumoto M., Nakamichi I., Kitagawa K., Shirane M., Tsunematsu R., Tsukiyama T., Ishida N., Kitagawa M., *Nakayama KI., Hatakeyama S.
 
(*Corresponding author)
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
EMBO J., 19: 2069-81, 2000.

No. 4, Times Cited: 532.

Yada M., Hatakeyama S., Kamura T., Nishiyama M., Tsunematsu R., Imaki H., Ishida N., Okumura F., Nakayama K., Nakayama KI.
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
EMBO J., 23: 2116-25, 2004.

No. 5, Times Cited: 444.

Kitagawa M., Hatakeyama S., Shirane M., Matsumoto M., Ishida N., Hattori K., Nakamichi I., Kikuchi A., Nakayama KI., Nakayama K.
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin.
EMBO J., 18: 2401-10, 1999.

No. 6, Times Cited: 417.

Takai H., Tominaga K., Motoyama N., Minamishima YA., Nagahama H., Tsukiyama T., Ikeda K., Nakayama K., Nakanishi M., Nakayama KI.
Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice.
Genes Dev., 14: 1439-47, 2000.

No. 7, Times Cited: 416.

Hatakeyama S., Yada M., Matsumoto M., Ishida N., Nakayama KI.
U box proteins as a new family of ubiquitin-protein ligases.
J. Biol. Chem., 276: 33111-20, 2001.

No. 8, Times Cited: 377.

Nakayama KI., Nakayama K., Negishi I., Kuida K., Shinkai Y., Louie MC., Fields LE., Lucas PJ., Stewart V., Alt FW., Loh DY.
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice.
Science, 261: 1584-8, 1993.

No. 9, Times Cited: 357.

Nakayama K., Nakayama KI., Negishi I., Kuida K., Sawa H., Loh DY.
Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.
Proc. Natl. Acad. Sci. U.S.A., 91: 3700-4, 1994.

No. 10, Times Cited: 325.

Kamura T., Hara T., Matsumoto M., Ishida N., Okumura F., Hatakeyama S., Yoshida M., Nakayama K., Nakayama KI.
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.
Nature Cell Biol., 6: 1229-35, 2004.